Ikuru is a boy who doesn't have long to live. Growing up questioning the purpose of his life and the reason for his death, he's constantly confused and lonely. Now, learning that he hasn't long to live, he requests that a special "girl" called a AGH-RMS be given to him. These people are genetically made so that they help heal and ease the mental burdens of someone who hasn't long to live. This manga is cute, sad, and ultimately a story about life, death, and humanity.